| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | SCN2A | Thr1966 | TPEKTDMtPSTTSPP | phosphorylation down-regulates activity | 32599005 | SIGNOR-275748 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | SCN2A PThr1966 | phosphorylation down-regulates ⊣ | SCN2A | 32599005 | SIGNOR-275748 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation → down-regulates activity | SCN2A | SIGNOR-275748 |
