| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | GAD1 | Thr91 | RDARFRRtETDFSNL | phosphorylation down-regulates activity | 15147202 | SIGNOR-249264 |
| PKA | GAD1 | Thr91 | RDARFRRtETDFSNL | phosphorylation down-regulates activity | 15147202 | SIGNOR-276009 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | phosphorylation up-regulates → | GAD1 PThr91 | phosphorylation down-regulates ⊣ | GAD1 | 15147202 | SIGNOR-249264 |
| PKA | phosphorylation up-regulates → | GAD1 PThr91 | phosphorylation down-regulates ⊣ | GAD1 | 15147202 | SIGNOR-276009 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCE | phosphorylation → down-regulates activity | GAD1 | SIGNOR-249264 |
| PKA | phosphorylation → down-regulates activity | GAD1 | SIGNOR-276009 |