| Name | AGAP2 |
| ID | Q99490 |
| Role | substrate |
| Enzymatic Domains |
GLD 402-578 PROSITE-ProRule
PH 676-910 PROSITE-ProRule
Arf-GAP 931-1051 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | AGAP2 | Ser985 | THLSRVRsLDLDDWP | phosphorylation up-regulates | 19176382 | SIGNOR-183543 |
| CDK5 | AGAP2 | Ser279 | KSKTLDNsDLHPGPP | phosphorylation up-regulates | 18487454 | SIGNOR-178660 |
| FYN | AGAP2 | Tyr1038 | ESWIRAKyEQLLFLA | phosphorylation up-regulates | 16841086 | SIGNOR-147932 |
| AKT | AGAP2 | Ser985 | THLSRVRsLDLDDWP | phosphorylation up-regulates | 19176382 | SIGNOR-244132 |
| FYN | AGAP2 | Tyr1130 | QGRTALFyARQAGSQ | phosphorylation up-regulates | 16841086 | SIGNOR-147936 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | AGAP2 PSer985 | phosphorylation up-regulates → | AGAP2 | 19176382 | SIGNOR-183543 |
| CDK5 | phosphorylation up-regulates → | AGAP2 PSer279 | phosphorylation up-regulates → | AGAP2 | 18487454 | SIGNOR-178660 |
| FYN | phosphorylation up-regulates → | AGAP2 PTyr1038 | phosphorylation up-regulates → | AGAP2 | 16841086 | SIGNOR-147932 |
| AKT | phosphorylation up-regulates → | AGAP2 PSer985 | phosphorylation up-regulates → | AGAP2 | 19176382 | SIGNOR-244132 |
| FYN | phosphorylation up-regulates → | AGAP2 PTyr1130 | phosphorylation up-regulates → | AGAP2 | 16841086 | SIGNOR-147936 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation → up-regulates | AGAP2 | SIGNOR-183543 |
| CDK5 | phosphorylation → up-regulates | AGAP2 | SIGNOR-178660 |
| FYN | phosphorylation → up-regulates | AGAP2 | SIGNOR-147932 |
| AKT | phosphorylation → up-regulates | AGAP2 | SIGNOR-244132 |
| FYN | phosphorylation → up-regulates | AGAP2 | SIGNOR-147936 |