Entity Details

Name EYA3
ID Q99504
Role phosphatase
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
EYA3H2AXTyr143ATQASQEydephosphorylation
down-regulates		20965415SIGNOR-168927
EYA3Six1/Dach–dephosphorylation
up-regulates activity		14628042SIGNOR-238032
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EYA3dephosphorylation
down-regulates
⊣
H2AX
PTyr143		dephosphorylation
up-regulates
→		H2AX20965415SIGNOR-168927
Regulator Mechanism/Effect Target SIGNOR-ID
EYA3dephosphorylation
img/direct_inhibition.png
down-regulates 		H2AXSIGNOR-168927
EYA3dephosphorylation
→
up-regulates activity 		Six1/DachSIGNOR-238032