| Name | SORT1 |
| ID | Q99523 |
| Role | substrate |
| Enzymatic Domains |
Vps10p 98-742 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK3 | SORT1 | Ser793 | RFLVHRYsVLQQHAE | phosphorylation down-regulates activity | 31767632 | SIGNOR-273719 |
| PAK2 | SORT1 | Ser793 | RFLVHRYsVLQQHAE | phosphorylation down-regulates activity | 31767632 | SIGNOR-273717 |
| PAK1 | SORT1 | Ser793 | RFLVHRYsVLQQHAE | phosphorylation down-regulates activity | 31767632 | SIGNOR-273718 |
| CSNK2B | SORT1 | Ser825 | KSGYHDDsDEDLLE | phosphorylation up-regulates quantity by stabilization | 25805502 | SIGNOR-273636 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK3 | phosphorylation up-regulates → | SORT1 PSer793 | phosphorylation down-regulates ⊣ | SORT1 | 31767632 | SIGNOR-273719 |
| PAK2 | phosphorylation up-regulates → | SORT1 PSer793 | phosphorylation down-regulates ⊣ | SORT1 | 31767632 | SIGNOR-273717 |
| PAK1 | phosphorylation up-regulates → | SORT1 PSer793 | phosphorylation down-regulates ⊣ | SORT1 | 31767632 | SIGNOR-273718 |
| CSNK2B | phosphorylation up-regulates → | SORT1 PSer825 | phosphorylation up-regulates → | SORT1 | 25805502 | SIGNOR-273636 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK3 | phosphorylation → down-regulates activity | SORT1 | SIGNOR-273719 |
| PAK2 | phosphorylation → down-regulates activity | SORT1 | SIGNOR-273717 |
| PAK1 | phosphorylation → down-regulates activity | SORT1 | SIGNOR-273718 |
| CSNK2B | phosphorylation → up-regulates quantity by stabilization | SORT1 | SIGNOR-273636 |