| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | PHB2 | Ser39 | VAYGVREsVFTVEGG | phosphorylation down-regulates activity | 28555617 | SIGNOR-279256 |
| CAMK4 | PHB2 | Ser91 | RARPRKIsSPTGSKD | phosphorylation down-regulates | 21689744 | SIGNOR-174437 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | PHB2 PSer39 | phosphorylation down-regulates ⊣ | PHB2 | 28555617 | SIGNOR-279256 |
| CAMK4 | phosphorylation up-regulates → | PHB2 PSer91 | phosphorylation down-regulates ⊣ | PHB2 | 21689744 | SIGNOR-174437 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation → down-regulates activity | PHB2 | SIGNOR-279256 |
| CAMK4 | phosphorylation![]() down-regulates | PHB2 | SIGNOR-174437 |