| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | CDX2 | Ser291 | PVSSLQAsVPGSVPG | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250729 |
| GSK3B | CDX2 | Ser291 | PVSSLQAsVPGSVPG | phosphorylation unknown | 16027724 | SIGNOR-251229 |
| MAPK14 | CDX2 | Ser291 | PVSSLQAsVPGSVPG | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250094 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | CDX2 PSer291 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250729 |
| GSK3B | phosphorylation up-regulates → | CDX2 PSer291 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-251229 |
| MAPK14 | phosphorylation up-regulates → | CDX2 PSer291 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250094 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation![]() down-regulates quantity by destabilization | CDX2 | SIGNOR-250729 |
| GSK3B | phosphorylation → unknown | CDX2 | SIGNOR-251229 |
| MAPK14 | phosphorylation![]() down-regulates quantity by destabilization | CDX2 | SIGNOR-250094 |