| Name | PKMYT1 |
| ID | Q99640 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 110-359 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | PKMYT1 | – | phosphorylation up-regulates | 19204086 | SIGNOR-183899 | |
| PLK1 | PKMYT1 | Ser426 | CSLLLDSsLSSNWDD | phosphorylation unknown | 12738781 | SIGNOR-249207 |
| PLK1 | PKMYT1 | Thr495 | LLSLFEDtLDPT | phosphorylation unknown | 12738781 | SIGNOR-249208 |
| PLK1 | PKMYT1 | Ser426 | CSLLLDSsLSSNWDD | phosphorylation down-regulates activity | 12738781 | SIGNOR-263096 |
| PLK1 | PKMYT1 | Thr495 | LLSLFEDtLDPT | phosphorylation down-regulates activity | 12738781 | SIGNOR-263097 |
| CDK1 | PKMYT1 | – | phosphorylation down-regulates activity | 21325631 | SIGNOR-279600 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | phosphorylation up-regulates → | PKMYT1 PSer426 | phosphorylation down-regulates ⊣ | PKMYT1 | 12738781 | SIGNOR-249207 |
| PLK1 | phosphorylation up-regulates → | PKMYT1 PThr495 | phosphorylation down-regulates ⊣ | PKMYT1 | 12738781 | SIGNOR-249208 |
| PLK1 | phosphorylation up-regulates → | PKMYT1 PSer426 | phosphorylation down-regulates ⊣ | PKMYT1 | 12738781 | SIGNOR-263096 |
| PLK1 | phosphorylation up-regulates → | PKMYT1 PThr495 | phosphorylation down-regulates ⊣ | PKMYT1 | 12738781 | SIGNOR-263097 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK8 | phosphorylation → up-regulates | PKMYT1 | SIGNOR-183899 |
| PLK1 | phosphorylation → unknown | PKMYT1 | SIGNOR-249207 |
| PLK1 | phosphorylation → unknown | PKMYT1 | SIGNOR-249208 |
| PLK1 | phosphorylation → down-regulates activity | PKMYT1 | SIGNOR-263096 |
| PLK1 | phosphorylation → down-regulates activity | PKMYT1 | SIGNOR-263097 |
| CDK1 | phosphorylation → down-regulates activity | PKMYT1 | SIGNOR-279600 |