| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | PKMYT1 | Thr495 | LLSLFEDtLDPT | phosphorylation unknown | 12738781 | SIGNOR-249208 |
| PLK1 | PKMYT1 | Thr495 | LLSLFEDtLDPT | phosphorylation down-regulates activity | 12738781 | SIGNOR-263097 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | phosphorylation up-regulates → | PKMYT1 PThr495 | phosphorylation down-regulates ⊣ | PKMYT1 | 12738781 | SIGNOR-249208 |
| PLK1 | phosphorylation up-regulates → | PKMYT1 PThr495 | phosphorylation down-regulates ⊣ | PKMYT1 | 12738781 | SIGNOR-263097 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK1 | phosphorylation → unknown | PKMYT1 | SIGNOR-249208 |
| PLK1 | phosphorylation → down-regulates activity | PKMYT1 | SIGNOR-263097 |