Entity Details

Name RBBP8
ID Q99708
Role substrate
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ATMRBBP8Ser664IDPGADLsQYKMDVTphosphorylation
down-regulates
10910365SIGNOR-79872
PKMRBBP8Thr126ELMNERNtLQEENKKphosphorylation
up-regulates activity
30297868SIGNOR-277413
ATRRBBP8Thr859WEVGFPStQTCMERGphosphorylation
up-regulates
23273981SIGNOR-200245
ATMRBBP8Ser745SCLADSFsQAADEEEphosphorylation
down-regulates
10910365SIGNOR-79876
CyclinA2/CDK2RBBP8Ser327 ELPTRVSsPVFGATSphosphorylation
up-regulates activity
15485915SIGNOR-263227
CDK2RBBP8Thr847FRYIPPNtPENFWEVphosphorylation
up-regulates
19202191SIGNOR-183840
PLK1RBBP8phosphorylation
up-regulates activity
30202980SIGNOR-279253
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ATMphosphorylation
up-regulates
RBBP8
PSer664
phosphorylation
down-regulates
RBBP810910365SIGNOR-79872
PKMphosphorylation
up-regulates
RBBP8
PThr126
phosphorylation
up-regulates
RBBP830297868SIGNOR-277413
ATRphosphorylation
up-regulates
RBBP8
PThr859
phosphorylation
up-regulates
RBBP823273981SIGNOR-200245
ATMphosphorylation
up-regulates
RBBP8
PSer745
phosphorylation
down-regulates
RBBP810910365SIGNOR-79876
CyclinA2/CDK2phosphorylation
up-regulates
RBBP8
PSer327
phosphorylation
up-regulates
RBBP815485915SIGNOR-263227
CDK2phosphorylation
up-regulates
RBBP8
PThr847
phosphorylation
up-regulates
RBBP819202191SIGNOR-183840
Regulator Mechanism/Effect Target SIGNOR-ID
ATMphosphorylation
img/direct_inhibition.png
down-regulates
RBBP8SIGNOR-79872
PKMphosphorylation

up-regulates activity
RBBP8SIGNOR-277413
ATRphosphorylation

up-regulates
RBBP8SIGNOR-200245
ATMphosphorylation
img/direct_inhibition.png
down-regulates
RBBP8SIGNOR-79876
CyclinA2/CDK2phosphorylation

up-regulates activity
RBBP8SIGNOR-263227
CDK2phosphorylation

up-regulates
RBBP8SIGNOR-183840
PLK1phosphorylation

up-regulates activity
RBBP8SIGNOR-279253