Entity Details

Name CDK2_Ser74
ID Q99741
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK2CDC6Ser74TPHLPPCsPPKQGKKphosphorylation
down-regulates activity		9889196SIGNOR-63895
CDK2CDC6Ser74TPHLPPCsPPKQGKKphosphorylation
down-regulates activity		10339564SIGNOR-67548
CyclinA2/CDK2CDC6Ser74TPHLPPCsPPKQGKKphosphorylation
down-regulates activity		9889196SIGNOR-217332
CyclinA2/CDK2CDC6Ser74TPHLPPCsPPKQGKKphosphorylation
down-regulates activity		10339564SIGNOR-217280
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK2phosphorylation
up-regulates
→
CDC6
PSer74		phosphorylation
down-regulates
⊣		CDC69889196SIGNOR-63895
CDK2phosphorylation
up-regulates
→
CDC6
PSer74		phosphorylation
down-regulates
⊣		CDC610339564SIGNOR-67548
CyclinA2/CDK2phosphorylation
up-regulates
→
CDC6
PSer74		phosphorylation
down-regulates
⊣		CDC69889196SIGNOR-217332
CyclinA2/CDK2phosphorylation
up-regulates
→
CDC6
PSer74		phosphorylation
down-regulates
⊣		CDC610339564SIGNOR-217280
Regulator Mechanism/Effect Target SIGNOR-ID
CDK2phosphorylation
→
down-regulates activity 		CDC6SIGNOR-63895
CDK2phosphorylation
→
down-regulates activity 		CDC6SIGNOR-67548
CyclinA2/CDK2phosphorylation
→
down-regulates activity 		CDC6SIGNOR-217332
CyclinA2/CDK2phosphorylation
→
down-regulates activity 		CDC6SIGNOR-217280