| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | CDC6 | Ser106 | DNQLTIKsPSKRELA | phosphorylation up-regulates | 10339564 | SIGNOR-217272 |
| CDK2 | CDC6 | Ser106 | DNQLTIKsPSKRELA | phosphorylation up-regulates | 10339564 | SIGNOR-67540 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation up-regulates → | CDC6 PSer106 | phosphorylation up-regulates → | CDC6 | 10339564 | SIGNOR-217272 |
| CDK2 | phosphorylation up-regulates → | CDC6 PSer106 | phosphorylation up-regulates → | CDC6 | 10339564 | SIGNOR-67540 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation → up-regulates | CDC6 | SIGNOR-217272 |
| CDK2 | phosphorylation → up-regulates | CDC6 | SIGNOR-67540 |
