Entity Details

Name DYRK1B_Ser185
ID Q99801
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LIMK2NKX3-1Ser185KTKRKQLsSELGDLEphosphorylation
down-regulates activity		34066036SIGNOR-278951
DYRK1BNKX3-1Ser185KTKRKQLsSELGDLEphosphorylation
down-regulates quantity by destabilization		25777618SIGNOR-279610
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LIMK2phosphorylation
up-regulates
→
NKX3-1
PSer185		phosphorylation
down-regulates
⊣		NKX3-134066036SIGNOR-278951
DYRK1Bphosphorylation
up-regulates
→
NKX3-1
PSer185		phosphorylation
down-regulates
⊣		NKX3-125777618SIGNOR-279610
Regulator Mechanism/Effect Target SIGNOR-ID
LIMK2phosphorylation
→
down-regulates activity 		NKX3-1SIGNOR-278951
DYRK1Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		NKX3-1SIGNOR-279610