| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTEN | NKX3-1 | Thr179 | FQNRRYKtKRKQLSS | dephosphorylation up-regulates quantity by stabilization | 31213464 | SIGNOR-277026 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTEN | dephosphorylation down-regulates ⊣ | NKX3-1 PThr179 | dephosphorylation down-regulates ⊣ | NKX3-1 | 31213464 | SIGNOR-277026 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTEN | dephosphorylation → up-regulates quantity by stabilization | NKX3-1 | SIGNOR-277026 |