| Name | VRK1 |
| ID | Q99986 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 37-317 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK3 | VRK1 | Ser342 | DDGKLDLsVVENGGL | phosphorylation up-regulates | 19103756 | SIGNOR-182858 |
| PRKCD | VRK1 | Thr355 | GLKAKTItKKRKKEI | phosphorylation down-regulates activity | 21346188 | SIGNOR-278219 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK3 | phosphorylation up-regulates → | VRK1 PSer342 | phosphorylation up-regulates → | VRK1 | 19103756 | SIGNOR-182858 |
| PRKCD | phosphorylation up-regulates → | VRK1 PThr355 | phosphorylation down-regulates ⊣ | VRK1 | 21346188 | SIGNOR-278219 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK3 | phosphorylation → up-regulates | VRK1 | SIGNOR-182858 |
| PRKCD | phosphorylation → down-regulates activity | VRK1 | SIGNOR-278219 |