Entity Details

Name GORASP1
ID Q9BQQ3
Role substrate
Enzymatic Domains
PDZ GRASP-type 1 15-105
PROSITE-ProRule
PDZ GRASP-type 2 111-199
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinB/CDK1GORASP1Ser373FEVSFLDsPGAQAQAphosphorylation
down-regulates activity		15678101SIGNOR-260606
ERK1/2GORASP1Ser274DPLPGPGsPSHSAPDphosphorylation
down-regulates activity		18762583SIGNOR-260605
MAPK1GORASP1Ser274DPLPGPGsPSHSAPDphosphorylation
down-regulates activity		15834132SIGNOR-262841
PLK1GORASP1–phosphorylation
down-regulates quantity		20214750SIGNOR-279554
CDK1GORASP1Ser274DPLPGPGsPSHSAPDphosphorylation
down-regulates activity		15834132SIGNOR-262840
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinB/CDK1phosphorylation
up-regulates
→
GORASP1
PSer373		phosphorylation
down-regulates
⊣		GORASP115678101SIGNOR-260606
ERK1/2phosphorylation
up-regulates
→
GORASP1
PSer274		phosphorylation
down-regulates
⊣		GORASP118762583SIGNOR-260605
MAPK1phosphorylation
up-regulates
→
GORASP1
PSer274		phosphorylation
down-regulates
⊣		GORASP115834132SIGNOR-262841
CDK1phosphorylation
up-regulates
→
GORASP1
PSer274		phosphorylation
down-regulates
⊣		GORASP115834132SIGNOR-262840
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinB/CDK1phosphorylation
→
down-regulates activity 		GORASP1SIGNOR-260606
ERK1/2phosphorylation
→
down-regulates activity 		GORASP1SIGNOR-260605
MAPK1phosphorylation
→
down-regulates activity 		GORASP1SIGNOR-262841
PLK1phosphorylation
→
down-regulates quantity 		GORASP1SIGNOR-279554
CDK1phosphorylation
→
down-regulates activity 		GORASP1SIGNOR-262840