| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ERK1/2 | RAMAC | Ser36 | YLKRPPEsPPIVEEW | phosphorylation down-regulates quantity by destabilization | 27452456 | SIGNOR-277267 |
| ERK1/2 | RAMAC | Ser36 | YLKRPPEsPPIVEEW | phosphorylation down-regulates quantity by destabilization | 27452456 | SIGNOR-277819 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ERK1/2 | phosphorylation up-regulates → | RAMAC PSer36 | phosphorylation down-regulates ⊣ | RAMAC | 27452456 | SIGNOR-277267 |
| ERK1/2 | phosphorylation up-regulates → | RAMAC PSer36 | phosphorylation down-regulates ⊣ | RAMAC | 27452456 | SIGNOR-277819 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ERK1/2 | phosphorylation![]() down-regulates quantity by destabilization | RAMAC | SIGNOR-277267 |
| ERK1/2 | phosphorylation![]() down-regulates quantity by destabilization | RAMAC | SIGNOR-277819 |