| Name | DUSP26 |
| ID | Q9BV47 |
| Role | phosphatase |
| Enzymatic Domains |
Tyrosine-protein phosphatase 60-207 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DUSP26 | NTRK1 | – | dephosphorylation down-regulates activity | 28701747 | SIGNOR-277105 | |
| DUSP26 | TP53 | Ser20 | PLSQETFsDLWKLLP | dephosphorylation down-regulates | 20562916 | SIGNOR-166258 |
| DUSP26 | TP53 | Ser37 | NVLSPLPsQAMDDLM | dephosphorylation down-regulates | 20562916 | SIGNOR-166262 |
| DUSP26 | TP53 | Ser20 | PLSQETFsDLWKLLP | dephosphorylation down-regulates activity | 20562916 | SIGNOR-248765 |
| DUSP26 | TP53 | Ser37 | NVLSPLPsQAMDDLM | dephosphorylation down-regulates activity | 20562916 | SIGNOR-248766 |
| DUSP26 | FGFR1 | – | dephosphorylation down-regulates activity | 28701747 | SIGNOR-277104 | |
| DUSP26 | FADD | Ser194 | QNRSGAMsPMSWNSD | dephosphorylation down-regulates activity | 24548998 | SIGNOR-204559 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DUSP26 | dephosphorylation down-regulates ⊣ | TP53 PSer20 | dephosphorylation up-regulates → | TP53 | 20562916 | SIGNOR-166258 |
| DUSP26 | dephosphorylation down-regulates ⊣ | TP53 PSer37 | dephosphorylation up-regulates → | TP53 | 20562916 | SIGNOR-166262 |
| DUSP26 | dephosphorylation down-regulates ⊣ | TP53 PSer20 | dephosphorylation up-regulates → | TP53 | 20562916 | SIGNOR-248765 |
| DUSP26 | dephosphorylation down-regulates ⊣ | TP53 PSer37 | dephosphorylation up-regulates → | TP53 | 20562916 | SIGNOR-248766 |
| DUSP26 | dephosphorylation down-regulates ⊣ | FADD PSer194 | dephosphorylation up-regulates → | FADD | 24548998 | SIGNOR-204559 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DUSP26 | dephosphorylation → down-regulates activity | NTRK1 | SIGNOR-277105 |
| DUSP26 | dephosphorylation down-regulates | TP53 | SIGNOR-166258 |
| DUSP26 | dephosphorylation down-regulates | TP53 | SIGNOR-166262 |
| DUSP26 | dephosphorylation → down-regulates activity | TP53 | SIGNOR-248765 |
| DUSP26 | dephosphorylation → down-regulates activity | TP53 | SIGNOR-248766 |
| DUSP26 | dephosphorylation → down-regulates activity | FGFR1 | SIGNOR-277104 |
| DUSP26 | dephosphorylation → down-regulates activity | FADD | SIGNOR-204559 |