| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NEK2 | CEP250 | Ser2394 | LHHSLSHsLLAVAQA | phosphorylation down-regulates | 24695856 | SIGNOR-204837 |
| SIK2 | CEP250 | Ser2394 | LHHSLSHsLLAVAQA | phosphorylation unknown | 20708153 | SIGNOR-167492 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NEK2 | phosphorylation up-regulates → | CEP250 PSer2394 | phosphorylation down-regulates ⊣ | CEP250 | 24695856 | SIGNOR-204837 |
| SIK2 | phosphorylation up-regulates → | CEP250 PSer2394 | phosphorylation down-regulates ⊣ | CEP250 | 20708153 | SIGNOR-167492 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| NEK2 | phosphorylation down-regulates | CEP250 | SIGNOR-204837 |
| SIK2 | phosphorylation → unknown | CEP250 | SIGNOR-167492 |
