| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | PHF20 | Ser291 | ELRRRKIsKGCEVPL | phosphorylation down-regulates | 22334668 | SIGNOR-196112 |
| AKT1 | PHF20 | Ser291 | ELRRRKIsKGCEVPL | phosphorylation down-regulates | 22334668 | SIGNOR-252529 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | phosphorylation up-regulates → | PHF20 PSer291 | phosphorylation down-regulates ⊣ | PHF20 | 22334668 | SIGNOR-196112 |
| AKT1 | phosphorylation up-regulates → | PHF20 PSer291 | phosphorylation down-regulates ⊣ | PHF20 | 22334668 | SIGNOR-252529 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT | phosphorylation![]() down-regulates | PHF20 | SIGNOR-196112 |
| AKT1 | phosphorylation![]() down-regulates | PHF20 | SIGNOR-252529 |