Entity Details

Name TRPM6
ID Q9BX84
Role kinase
Enzymatic Domains
Alpha-type protein kinase 1750-1980
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TRPM6H2AC11Ser2sGRGKQGGphosphorylation
down-regulates activity		15010469SIGNOR-276008
TRPM6TRPM7–phosphorylation
down-regulates quantity		24858416SIGNOR-279770
TRPM6TRPM6Thr1851FNQVKPQtIPYTPRFphosphorylation
down-regulates activity		18258429SIGNOR-260922
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TRPM6phosphorylation
up-regulates
→
H2AC11
PSer2		phosphorylation
down-regulates
⊣		H2AC1115010469SIGNOR-276008
TRPM6phosphorylation
up-regulates
→
TRPM6
PThr1851		phosphorylation
down-regulates
⊣		TRPM618258429SIGNOR-260922
Regulator Mechanism/Effect Target SIGNOR-ID
TRPM6phosphorylation
→
down-regulates activity 		H2AC11SIGNOR-276008
TRPM6phosphorylation
→
down-regulates quantity 		TRPM7SIGNOR-279770
TRPM6phosphorylation
→
down-regulates activity 		TRPM6SIGNOR-260922