Entity Details

Name PPP2CA_Ser644
ID Q9BXL7
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP2CACARD11Ser644NLMFRKFsLERPFRPdephosphorylation
down-regulates activity		21157432SIGNOR-248650
AKT1CARD11Ser644NLMFRKFsLERPFRPphosphorylation
up-regulates activity		24548923SIGNOR-276255
AKT1CARD11Ser644NLMFRKFsLERPFRPphosphorylation
up-regulates activity		24548923SIGNOR-276621
PPP2CBCARD11Ser644NLMFRKFsLERPFRPdephosphorylation
down-regulates activity		21157432SIGNOR-248607
PRKCQCARD11Ser644NLMFRKFsLERPFRPphosphorylation
up-regulates activity		21157432SIGNOR-249193
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP2CAdephosphorylation
down-regulates
⊣
CARD11
PSer644		dephosphorylation
up-regulates
→		CARD1121157432SIGNOR-248650
AKT1phosphorylation
up-regulates
→
CARD11
PSer644		phosphorylation
up-regulates
→		CARD1124548923SIGNOR-276255
AKT1phosphorylation
up-regulates
→
CARD11
PSer644		phosphorylation
up-regulates
→		CARD1124548923SIGNOR-276621
PPP2CBdephosphorylation
down-regulates
⊣
CARD11
PSer644		dephosphorylation
up-regulates
→		CARD1121157432SIGNOR-248607
PRKCQphosphorylation
up-regulates
→
CARD11
PSer644		phosphorylation
up-regulates
→		CARD1121157432SIGNOR-249193
Regulator Mechanism/Effect Target SIGNOR-ID
PPP2CAdephosphorylation
→
down-regulates activity 		CARD11SIGNOR-248650
AKT1phosphorylation
→
up-regulates activity 		CARD11SIGNOR-276255
AKT1phosphorylation
→
up-regulates activity 		CARD11SIGNOR-276621
PPP2CBdephosphorylation
→
down-regulates activity 		CARD11SIGNOR-248607
PRKCQphosphorylation
→
up-regulates activity 		CARD11SIGNOR-249193