| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | HDAC8 | Ser39 | AKIPKRAsMVHSLIE | phosphorylation down-regulates | 14701748 | SIGNOR-120643 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | HDAC8 PSer39 | phosphorylation down-regulates ⊣ | HDAC8 | 14701748 | SIGNOR-120643 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation down-regulates | HDAC8 | SIGNOR-120643 |
