Entity Details

Name IRX2
ID Q9BZI1
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1IRX2Ser46SASGSAFsPYPGSAAphosphorylation
up-regulates activity		15133517SIGNOR-263052
MAPK3IRX2Ser325PGAPPPAsKPKLWSLphosphorylation
up-regulates activity		15133517SIGNOR-263061
MAPK3IRX2Ser317
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TPQGSRTsPGAPPPAphosphorylation
up-regulates activity		15133517SIGNOR-263060
GbetaIRX2–phosphorylation
up-regulates activity		15133517SIGNOR-270097
MAPK1IRX2Ser64QAATGFGsPLQYSADphosphorylation
up-regulates activity		15133517SIGNOR-263053
ERK1/2IRX2–phosphorylation
up-regulates activity		15133517SIGNOR-270193
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
IRX2
PSer46		phosphorylation
up-regulates
→		IRX215133517SIGNOR-263052
MAPK3phosphorylation
up-regulates
→
IRX2
PSer325		phosphorylation
up-regulates
→		IRX215133517SIGNOR-263061
MAPK3phosphorylation
up-regulates
→
IRX2
PSer317		phosphorylation
up-regulates
→		IRX215133517SIGNOR-263060
MAPK1phosphorylation
up-regulates
→
IRX2
PSer64		phosphorylation
up-regulates
→		IRX215133517SIGNOR-263053
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
up-regulates activity 		IRX2SIGNOR-263052
MAPK3phosphorylation
→
up-regulates activity 		IRX2SIGNOR-263061
MAPK3phosphorylation
→
up-regulates activity 		IRX2SIGNOR-263060
Gbetaphosphorylation
→
up-regulates activity 		IRX2SIGNOR-270097
MAPK1phosphorylation
→
up-regulates activity 		IRX2SIGNOR-263053
ERK1/2phosphorylation
→
up-regulates activity 		IRX2SIGNOR-270193