| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | PPP1R12C | Ser452 | AGLQRSAsSSWLEGT | phosphorylation down-regulates | 22137581 | SIGNOR-216600 |
| PRKAA2 | PPP1R12C | Ser452 | AGLQRSAsSSWLEGT | phosphorylation down-regulates | 22137581 | SIGNOR-195148 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | phosphorylation up-regulates → | PPP1R12C PSer452 | phosphorylation down-regulates ⊣ | PPP1R12C | 22137581 | SIGNOR-216600 |
| PRKAA2 | phosphorylation up-regulates → | PPP1R12C PSer452 | phosphorylation down-regulates ⊣ | PPP1R12C | 22137581 | SIGNOR-195148 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AMPK | phosphorylation![]() down-regulates | PPP1R12C | SIGNOR-216600 |
| PRKAA2 | phosphorylation![]() down-regulates | PPP1R12C | SIGNOR-195148 |