| Name | PRKD2 |
| ID | Q9BZL6 |
| Role | substrate |
| Enzymatic Domains |
PH 397-509 PROSITE-ProRule
Protein kinase 551-807 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCH | PRKD2 | Ser706 | ARIIGEKsFRRSVVG | phosphorylation up-regulates | 12058027 | SIGNOR-89423 |
| PRKD2 | PRKD2 | Ser876 | QGLAERIsVL | phosphorylation up-regulates | 11062248 | SIGNOR-83834 |
| PKA | PRKD2 | Ser876 | QGLAERIsVL | phosphorylation up-regulates activity | 12058027 | SIGNOR-275950 |
| PRKCH | PRKD2 | Ser706 | ARIIGEKsFRRSVVG | phosphorylation up-regulates activity | 12058027 | SIGNOR-275958 |
| PRKCE | PRKD2 | Ser876 | QGLAERIsVL | phosphorylation up-regulates activity | 12058027 | SIGNOR-275959 |
| PRKCH | PRKD2 | Ser876 | QGLAERIsVL | phosphorylation up-regulates activity | 12058027 | SIGNOR-275956 |
| PRKCE | PRKD2 | Ser710 | GEKSFRRsVVGTPAY | phosphorylation up-regulates | 12058027 | SIGNOR-89415 |
| PKA | PRKD2 | Ser710 | GEKSFRRsVVGTPAY | phosphorylation up-regulates activity | 12058027 | SIGNOR-275951 |
| PRKCH | PRKD2 | Ser710 | GEKSFRRsVVGTPAY | phosphorylation up-regulates | 12058027 | SIGNOR-89427 |
| PRKCA | PRKD2 | Ser710 | GEKSFRRsVVGTPAY | phosphorylation up-regulates activity | 12058027 | SIGNOR-275954 |
| PRKCA | PRKD2 | Ser706 | ARIIGEKsFRRSVVG | phosphorylation up-regulates activity | 12058027 | SIGNOR-275955 |
| PRKCE | PRKD2 | Ser710 | GEKSFRRsVVGTPAY | phosphorylation up-regulates activity | 12058027 | SIGNOR-275960 |
| PRKCE | PRKD2 | Ser876 | QGLAERIsVL | phosphorylation up-regulates | 12058027 | SIGNOR-89419 |
| PRKCE | PRKD2 | Ser706 | ARIIGEKsFRRSVVG | phosphorylation up-regulates | 12058027 | SIGNOR-89411 |
| PRKCH | PRKD2 | Ser710 | GEKSFRRsVVGTPAY | phosphorylation up-regulates activity | 12058027 | SIGNOR-275957 |
| PRKCE | PRKD2 | Ser706 | ARIIGEKsFRRSVVG | phosphorylation up-regulates activity | 12058027 | SIGNOR-275961 |
| PKA | PRKD2 | Ser706 | ARIIGEKsFRRSVVG | phosphorylation up-regulates activity | 12058027 | SIGNOR-275952 |
| PRKCA | PRKD2 | Ser876 | QGLAERIsVL | phosphorylation up-regulates activity | 12058027 | SIGNOR-275953 |
| PRKCH | PRKD2 | Ser876 | QGLAERIsVL | phosphorylation up-regulates | 12058027 | SIGNOR-89431 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCH | phosphorylation up-regulates → | PRKD2 PSer706 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-89423 |
| PRKD2 | phosphorylation up-regulates → | PRKD2 PSer876 | phosphorylation up-regulates → | PRKD2 | 11062248 | SIGNOR-83834 |
| PKA | phosphorylation up-regulates → | PRKD2 PSer876 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275950 |
| PRKCH | phosphorylation up-regulates → | PRKD2 PSer706 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275958 |
| PRKCE | phosphorylation up-regulates → | PRKD2 PSer876 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275959 |
| PRKCH | phosphorylation up-regulates → | PRKD2 PSer876 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275956 |
| PRKCE | phosphorylation up-regulates → | PRKD2 PSer710 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-89415 |
| PKA | phosphorylation up-regulates → | PRKD2 PSer710 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275951 |
| PRKCH | phosphorylation up-regulates → | PRKD2 PSer710 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-89427 |
| PRKCA | phosphorylation up-regulates → | PRKD2 PSer710 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275954 |
| PRKCA | phosphorylation up-regulates → | PRKD2 PSer706 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275955 |
| PRKCE | phosphorylation up-regulates → | PRKD2 PSer710 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275960 |
| PRKCE | phosphorylation up-regulates → | PRKD2 PSer876 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-89419 |
| PRKCE | phosphorylation up-regulates → | PRKD2 PSer706 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-89411 |
| PRKCH | phosphorylation up-regulates → | PRKD2 PSer710 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275957 |
| PRKCE | phosphorylation up-regulates → | PRKD2 PSer706 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275961 |
| PKA | phosphorylation up-regulates → | PRKD2 PSer706 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275952 |
| PRKCA | phosphorylation up-regulates → | PRKD2 PSer876 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-275953 |
| PRKCH | phosphorylation up-regulates → | PRKD2 PSer876 | phosphorylation up-regulates → | PRKD2 | 12058027 | SIGNOR-89431 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCH | phosphorylation → up-regulates | PRKD2 | SIGNOR-89423 |
| PRKD2 | phosphorylation → up-regulates | PRKD2 | SIGNOR-83834 |
| PKA | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275950 |
| PRKCH | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275958 |
| PRKCE | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275959 |
| PRKCH | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275956 |
| PRKCE | phosphorylation → up-regulates | PRKD2 | SIGNOR-89415 |
| PKA | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275951 |
| PRKCH | phosphorylation → up-regulates | PRKD2 | SIGNOR-89427 |
| PRKCA | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275954 |
| PRKCA | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275955 |
| PRKCE | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275960 |
| PRKCE | phosphorylation → up-regulates | PRKD2 | SIGNOR-89419 |
| PRKCE | phosphorylation → up-regulates | PRKD2 | SIGNOR-89411 |
| PRKCH | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275957 |
| PRKCE | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275961 |
| PKA | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275952 |
| PRKCA | phosphorylation → up-regulates activity | PRKD2 | SIGNOR-275953 |
| PRKCH | phosphorylation → up-regulates | PRKD2 | SIGNOR-89431 |