Entity Details

Name CyclinB/CDK1_Ser90
ID Q9GZV5
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1WWTR1Ser90QHVRSHSsPASLQLGphosphorylation
down-regulates quantity by destabilization		26183396SIGNOR-276926
CDK1WWTR1Ser90QHVRSHSsPASLQLGphosphorylation
down-regulates activity		26375055SIGNOR-276518
CyclinB/CDK1WWTR1Ser90QHVRSHSsPASLQLGphosphorylation
down-regulates activity		26375055SIGNOR-276522
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
WWTR1
PSer90		phosphorylation
down-regulates
⊣		WWTR126183396SIGNOR-276926
CDK1phosphorylation
up-regulates
→
WWTR1
PSer90		phosphorylation
down-regulates
⊣		WWTR126375055SIGNOR-276518
CyclinB/CDK1phosphorylation
up-regulates
→
WWTR1
PSer90		phosphorylation
down-regulates
⊣		WWTR126375055SIGNOR-276522
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		WWTR1SIGNOR-276926
CDK1phosphorylation
→
down-regulates activity 		WWTR1SIGNOR-276518
CyclinB/CDK1phosphorylation
→
down-regulates activity 		WWTR1SIGNOR-276522