| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKD1 | MFF | Ser155 | GRLKRERsMSENAVR | phosphorylation up-regulates activity | 34010649 | SIGNOR-277558 |
| PRKAA1 | MFF | Ser155 | GRLKRERsMSENAVR | phosphorylation up-regulates activity | 26816379 | SIGNOR-245953 |
| PRKD1 | MFF | Ser155 | GRLKRERsMSENAVR | phosphorylation up-regulates activity | 34010649 | SIGNOR-275943 |
| PRKD3 | MFF | Ser172 | GQLVRNDsLWHRSDS | phosphorylation up-regulates activity | 34010649 | SIGNOR-275940 |
| PRKD3 | MFF | Ser155 | GRLKRERsMSENAVR | phosphorylation up-regulates activity | 34010649 | SIGNOR-275945 |
| PRKD1 | MFF | Ser172 | GQLVRNDsLWHRSDS | phosphorylation up-regulates activity | 34010649 | SIGNOR-277559 |
| PRKD1 | MFF | Ser275 | DNVRYGIsNIDTTIE | phosphorylation up-regulates activity | 34010649 | SIGNOR-275948 |
| AMPK | MFF | Ser155 | GRLKRERsMSENAVR | phosphorylation up-regulates activity | 26816379 | SIGNOR-245948 |
| AMPK | MFF | Ser172 | GQLVRNDsLWHRSDS | phosphorylation up-regulates activity | 26816379 | SIGNOR-249655 |
| PRKAA1 | MFF | Ser172 | GQLVRNDsLWHRSDS | phosphorylation up-regulates activity | 26816379 | SIGNOR-249656 |
| PRKD3 | MFF | Ser275 | DNVRYGIsNIDTTIE | phosphorylation up-regulates activity | 34010649 | SIGNOR-275946 |
| PRKD1 | MFF | Ser172 | GQLVRNDsLWHRSDS | phosphorylation up-regulates activity | 34010649 | SIGNOR-275942 |
| PRKD2 | MFF | Ser172 | GQLVRNDsLWHRSDS | phosphorylation up-regulates activity | 34010649 | SIGNOR-275941 |
| PRKD2 | MFF | Ser155 | GRLKRERsMSENAVR | phosphorylation up-regulates activity | 34010649 | SIGNOR-275947 |
| PRKD2 | MFF | Ser275 | DNVRYGIsNIDTTIE | phosphorylation up-regulates activity | 34010649 | SIGNOR-275949 |
| PRKD1 | MFF | Ser275 | DNVRYGIsNIDTTIE | phosphorylation up-regulates activity | 34010649 | SIGNOR-277557 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKD1 | phosphorylation up-regulates → | MFF PSer155 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-277558 |
| PRKAA1 | phosphorylation up-regulates → | MFF PSer155 | phosphorylation up-regulates → | MFF | 26816379 | SIGNOR-245953 |
| PRKD1 | phosphorylation up-regulates → | MFF PSer155 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275943 |
| PRKD3 | phosphorylation up-regulates → | MFF PSer172 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275940 |
| PRKD3 | phosphorylation up-regulates → | MFF PSer155 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275945 |
| PRKD1 | phosphorylation up-regulates → | MFF PSer172 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-277559 |
| PRKD1 | phosphorylation up-regulates → | MFF PSer275 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275948 |
| AMPK | phosphorylation up-regulates → | MFF PSer155 | phosphorylation up-regulates → | MFF | 26816379 | SIGNOR-245948 |
| AMPK | phosphorylation up-regulates → | MFF PSer172 | phosphorylation up-regulates → | MFF | 26816379 | SIGNOR-249655 |
| PRKAA1 | phosphorylation up-regulates → | MFF PSer172 | phosphorylation up-regulates → | MFF | 26816379 | SIGNOR-249656 |
| PRKD3 | phosphorylation up-regulates → | MFF PSer275 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275946 |
| PRKD1 | phosphorylation up-regulates → | MFF PSer172 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275942 |
| PRKD2 | phosphorylation up-regulates → | MFF PSer172 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275941 |
| PRKD2 | phosphorylation up-regulates → | MFF PSer155 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275947 |
| PRKD2 | phosphorylation up-regulates → | MFF PSer275 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-275949 |
| PRKD1 | phosphorylation up-regulates → | MFF PSer275 | phosphorylation up-regulates → | MFF | 34010649 | SIGNOR-277557 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKD1 | phosphorylation → up-regulates activity | MFF | SIGNOR-277558 |
| PRKAA1 | phosphorylation → up-regulates activity | MFF | SIGNOR-245953 |
| PRKD1 | phosphorylation → up-regulates activity | MFF | SIGNOR-275943 |
| PRKD3 | phosphorylation → up-regulates activity | MFF | SIGNOR-275940 |
| PRKD3 | phosphorylation → up-regulates activity | MFF | SIGNOR-275945 |
| PRKD1 | phosphorylation → up-regulates activity | MFF | SIGNOR-277559 |
| PRKD1 | phosphorylation → up-regulates activity | MFF | SIGNOR-275948 |
| AMPK | phosphorylation → up-regulates activity | MFF | SIGNOR-245948 |
| AMPK | phosphorylation → up-regulates activity | MFF | SIGNOR-249655 |
| PRKAA1 | phosphorylation → up-regulates activity | MFF | SIGNOR-249656 |
| PRKD3 | phosphorylation → up-regulates activity | MFF | SIGNOR-275946 |
| PRKD1 | phosphorylation → up-regulates activity | MFF | SIGNOR-275942 |
| PRKD2 | phosphorylation → up-regulates activity | MFF | SIGNOR-275941 |
| PRKD2 | phosphorylation → up-regulates activity | MFF | SIGNOR-275947 |
| PRKD2 | phosphorylation → up-regulates activity | MFF | SIGNOR-275949 |
| PRKD1 | phosphorylation → up-regulates activity | MFF | SIGNOR-277557 |
