| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| mTORC1 | MAF1 | Ser60 | PHVLEALsPPQTSGL | phosphorylation down-regulates | 20516213 | SIGNOR-217149 |
| mTORC1 | MAF1 | Ser68 | PPQTSGLsPSRLSKS | phosphorylation down-regulates | 20516213 | SIGNOR-217145 |
| MTOR | MAF1 | Ser60 | PHVLEALsPPQTSGL | phosphorylation down-regulates | 20516213 | SIGNOR-165791 |
| MTOR | MAF1 | Ser68 | PPQTSGLsPSRLSKS | phosphorylation down-regulates | 20516213 | SIGNOR-165795 |
| MTOR | MAF1 | Ser75 | SPSRLSKsQGGEEEG | phosphorylation down-regulates | 20516213 | SIGNOR-165799 |
| MTOR | MAF1 | Ser75 | SPSRLSKsQGGEEEG | phosphorylation down-regulates | 20543138 | SIGNOR-166054 |
| MTOR | MAF1 | Ser75 | SPSRLSKsQGGEEEG | phosphorylation down-regulates | 20233713 | SIGNOR-164352 |
| MTOR | MAF1 | Ser68 | PPQTSGLsPSRLSKS | phosphorylation down-regulates | 20233713 | SIGNOR-164348 |
| mTORC1 | MAF1 | Ser75 | SPSRLSKsQGGEEEG | phosphorylation down-regulates | 20516213 | SIGNOR-217153 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| mTORC1 | phosphorylation up-regulates → | MAF1 PSer60 | phosphorylation down-regulates ⊣ | MAF1 | 20516213 | SIGNOR-217149 |
| mTORC1 | phosphorylation up-regulates → | MAF1 PSer68 | phosphorylation down-regulates ⊣ | MAF1 | 20516213 | SIGNOR-217145 |
| MTOR | phosphorylation up-regulates → | MAF1 PSer60 | phosphorylation down-regulates ⊣ | MAF1 | 20516213 | SIGNOR-165791 |
| MTOR | phosphorylation up-regulates → | MAF1 PSer68 | phosphorylation down-regulates ⊣ | MAF1 | 20516213 | SIGNOR-165795 |
| MTOR | phosphorylation up-regulates → | MAF1 PSer75 | phosphorylation down-regulates ⊣ | MAF1 | 20516213 | SIGNOR-165799 |
| MTOR | phosphorylation up-regulates → | MAF1 PSer75 | phosphorylation down-regulates ⊣ | MAF1 | 20543138 | SIGNOR-166054 |
| MTOR | phosphorylation up-regulates → | MAF1 PSer75 | phosphorylation down-regulates ⊣ | MAF1 | 20233713 | SIGNOR-164352 |
| MTOR | phosphorylation up-regulates → | MAF1 PSer68 | phosphorylation down-regulates ⊣ | MAF1 | 20233713 | SIGNOR-164348 |
| mTORC1 | phosphorylation up-regulates → | MAF1 PSer75 | phosphorylation down-regulates ⊣ | MAF1 | 20516213 | SIGNOR-217153 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| mTORC1 | phosphorylation down-regulates | MAF1 | SIGNOR-217149 |
| mTORC1 | phosphorylation down-regulates | MAF1 | SIGNOR-217145 |
| MTOR | phosphorylation down-regulates | MAF1 | SIGNOR-165791 |
| MTOR | phosphorylation down-regulates | MAF1 | SIGNOR-165795 |
| MTOR | phosphorylation down-regulates | MAF1 | SIGNOR-165799 |
| MTOR | phosphorylation down-regulates | MAF1 | SIGNOR-166054 |
| MTOR | phosphorylation down-regulates | MAF1 | SIGNOR-164352 |
| MTOR | phosphorylation down-regulates | MAF1 | SIGNOR-164348 |
| mTORC1 | phosphorylation down-regulates | MAF1 | SIGNOR-217153 |
