Entity Details

Name RACGAP1
ID Q9H0H5
Role substrate
Enzymatic Domains
Rho-GAP 349-539
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AURKBRACGAP1Thr145 AGNKRLStIDESGSIphosphorylation
up-regulates activity
14744859SIGNOR-250589
PLK1RACGAP1Thr260QPWNSDStLNSRQLEphosphorylation
up-regulates
19468302SIGNOR-185758
AURKBRACGAP1Ser187REKRRSTsRQFVDGPphosphorylation
up-regulates activity
14744859SIGNOR-250588
AURKBRACGAP1Thr186KREKRRStSRQFVDGphosphorylation
up-regulates activity
14744859SIGNOR-250590
PLK1RACGAP1Ser214AVDQGNEsIVAKTTVphosphorylation
up-regulates
19468302SIGNOR-185754
PPP2CARACGAP1Thr588PEHQLLKtPSSSSLSdephosphorylation
down-regulates
18201571SIGNOR-160402
AURKBRACGAP1Ser144NAGNKRLsTIDESGSphosphorylation
up-regulates activity
14744859SIGNOR-250586
AURKBRACGAP1Ser185KKREKRRsTSRQFVDphosphorylation
up-regulates activity
14744859SIGNOR-250587
PLK1RACGAP1Ser170ESLDWDSsLVKTFKLphosphorylation
up-regulates
19468302SIGNOR-185750
PPP2CARACGAP1Ser387ETGLYRIsGCDRTVKdephosphorylation
down-regulates
18201571SIGNOR-160398
PLK1RACGAP1Ser157GSILSDIsFDKTDESphosphorylation
up-regulates
19468302SIGNOR-185746
AURKBRACGAP1Ser387ETGLYRIsGCDRTVKphosphorylation
up-regulates activity
12689593SIGNOR-100569
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AURKBphosphorylation
up-regulates
RACGAP1
PThr145
phosphorylation
up-regulates
RACGAP114744859SIGNOR-250589
PLK1phosphorylation
up-regulates
RACGAP1
PThr260
phosphorylation
up-regulates
RACGAP119468302SIGNOR-185758
AURKBphosphorylation
up-regulates
RACGAP1
PSer187
phosphorylation
up-regulates
RACGAP114744859SIGNOR-250588
AURKBphosphorylation
up-regulates
RACGAP1
PThr186
phosphorylation
up-regulates
RACGAP114744859SIGNOR-250590
PLK1phosphorylation
up-regulates
RACGAP1
PSer214
phosphorylation
up-regulates
RACGAP119468302SIGNOR-185754
PPP2CAdephosphorylation
down-regulates
RACGAP1
PThr588
dephosphorylation
up-regulates
RACGAP118201571SIGNOR-160402
AURKBphosphorylation
up-regulates
RACGAP1
PSer144
phosphorylation
up-regulates
RACGAP114744859SIGNOR-250586
AURKBphosphorylation
up-regulates
RACGAP1
PSer185
phosphorylation
up-regulates
RACGAP114744859SIGNOR-250587
PLK1phosphorylation
up-regulates
RACGAP1
PSer170
phosphorylation
up-regulates
RACGAP119468302SIGNOR-185750
PPP2CAdephosphorylation
down-regulates
RACGAP1
PSer387
dephosphorylation
up-regulates
RACGAP118201571SIGNOR-160398
PLK1phosphorylation
up-regulates
RACGAP1
PSer157
phosphorylation
up-regulates
RACGAP119468302SIGNOR-185746
AURKBphosphorylation
up-regulates
RACGAP1
PSer387
phosphorylation
up-regulates
RACGAP112689593SIGNOR-100569
Regulator Mechanism/Effect Target SIGNOR-ID
AURKBphosphorylation

up-regulates activity
RACGAP1SIGNOR-250589
PLK1phosphorylation

up-regulates
RACGAP1SIGNOR-185758
AURKBphosphorylation

up-regulates activity
RACGAP1SIGNOR-250588
AURKBphosphorylation

up-regulates activity
RACGAP1SIGNOR-250590
PLK1phosphorylation

up-regulates
RACGAP1SIGNOR-185754
PPP2CAdephosphorylation
img/direct_inhibition.png
down-regulates
RACGAP1SIGNOR-160402
AURKBphosphorylation

up-regulates activity
RACGAP1SIGNOR-250586
AURKBphosphorylation

up-regulates activity
RACGAP1SIGNOR-250587
PLK1phosphorylation

up-regulates
RACGAP1SIGNOR-185750
PPP2CAdephosphorylation
img/direct_inhibition.png
down-regulates
RACGAP1SIGNOR-160398
PLK1phosphorylation

up-regulates
RACGAP1SIGNOR-185746
AURKBphosphorylation

up-regulates activity
RACGAP1SIGNOR-100569