| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | RACGAP1 | Ser387 | ETGLYRIsGCDRTVK | dephosphorylation down-regulates | 18201571 | SIGNOR-160398 |
| AURKB | RACGAP1 | Ser387 | ETGLYRIsGCDRTVK | phosphorylation up-regulates activity | 12689593 | SIGNOR-100569 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | dephosphorylation down-regulates ⊣ | RACGAP1 PSer387 | dephosphorylation up-regulates → | RACGAP1 | 18201571 | SIGNOR-160398 |
| AURKB | phosphorylation up-regulates → | RACGAP1 PSer387 | phosphorylation up-regulates → | RACGAP1 | 12689593 | SIGNOR-100569 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CA | dephosphorylation down-regulates | RACGAP1 | SIGNOR-160398 |
| AURKB | phosphorylation → up-regulates activity | RACGAP1 | SIGNOR-100569 |
