| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | ISCU | Ser14 | FRLRRAAsALLLRSP | phosphorylation up-regulates | 23508953 | SIGNOR-201595 |
| mTORC1 | ISCU | Ser14 | FRLRRAAsALLLRSP | phosphorylation up-regulates | 23508953 | SIGNOR-217082 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | phosphorylation up-regulates → | ISCU PSer14 | phosphorylation up-regulates → | ISCU | 23508953 | SIGNOR-201595 |
| mTORC1 | phosphorylation up-regulates → | ISCU PSer14 | phosphorylation up-regulates → | ISCU | 23508953 | SIGNOR-217082 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MTOR | phosphorylation → up-regulates | ISCU | SIGNOR-201595 |
| mTORC1 | phosphorylation → up-regulates | ISCU | SIGNOR-217082 |
