| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | KCNN2 | Ser568 | SSRRRRSsSTAPPTS | phosphorylation down-regulates | 16513649 | SIGNOR-145040 |
| PRKACA | KCNN2 | Ser464 | QAIHQLRsVKMEQRK | phosphorylation down-regulates | 16513649 | SIGNOR-145028 |
| PRKACA | KCNN2 | Ser569 | SRRRRSSsTAPPTSS | phosphorylation down-regulates | 16513649 | SIGNOR-145044 |
| PRKACA | KCNN2 | Ser567 | SSSRRRRsSSTAPPT | phosphorylation down-regulates | 16513649 | SIGNOR-145032 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | KCNN2 PSer568 | phosphorylation down-regulates ⊣ | KCNN2 | 16513649 | SIGNOR-145040 |
| PRKACA | phosphorylation up-regulates → | KCNN2 PSer464 | phosphorylation down-regulates ⊣ | KCNN2 | 16513649 | SIGNOR-145028 |
| PRKACA | phosphorylation up-regulates → | KCNN2 PSer569 | phosphorylation down-regulates ⊣ | KCNN2 | 16513649 | SIGNOR-145044 |
| PRKACA | phosphorylation up-regulates → | KCNN2 PSer567 | phosphorylation down-regulates ⊣ | KCNN2 | 16513649 | SIGNOR-145032 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation down-regulates | KCNN2 | SIGNOR-145040 |
| PRKACA | phosphorylation down-regulates | KCNN2 | SIGNOR-145028 |
| PRKACA | phosphorylation down-regulates | KCNN2 | SIGNOR-145044 |
| PRKACA | phosphorylation down-regulates | KCNN2 | SIGNOR-145032 |
