Entity Details

Name AMPK_Thr119
ID Q9H2X6
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AMPKHIPK2Thr119HNLMRRStVSLLDTYphosphorylation
down-regulates activity		23871434SIGNOR-275482
PRKAA2HIPK2Thr119HNLMRRStVSLLDTYphosphorylation
down-regulates activity		23871434SIGNOR-275485
PRKAA1HIPK2Thr119HNLMRRStVSLLDTYphosphorylation
up-regulates activity		23871434SIGNOR-276468
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AMPKphosphorylation
up-regulates
→
HIPK2
PThr119		phosphorylation
down-regulates
⊣		HIPK223871434SIGNOR-275482
PRKAA2phosphorylation
up-regulates
→
HIPK2
PThr119		phosphorylation
down-regulates
⊣		HIPK223871434SIGNOR-275485
PRKAA1phosphorylation
up-regulates
→
HIPK2
PThr119		phosphorylation
up-regulates
→		HIPK223871434SIGNOR-276468
Regulator Mechanism/Effect Target SIGNOR-ID
AMPKphosphorylation
→
down-regulates activity 		HIPK2SIGNOR-275482
PRKAA2phosphorylation
→
down-regulates activity 		HIPK2SIGNOR-275485
PRKAA1phosphorylation
→
up-regulates activity 		HIPK2SIGNOR-276468