Entity Details

Name HIPK2_Ser121
ID Q9H2X6
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKAA1HIPK2Ser121LMRRSTVsLLDTYQKphosphorylation
up-regulates activity		23871434SIGNOR-276467
AMPKHIPK2Ser121LMRRSTVsLLDTYQKphosphorylation
down-regulates activity		23871434SIGNOR-275483
PRKAA2HIPK2Ser121LMRRSTVsLLDTYQKphosphorylation
down-regulates activity		23871434SIGNOR-275486
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKAA1phosphorylation
up-regulates
→
HIPK2
PSer121		phosphorylation
up-regulates
→		HIPK223871434SIGNOR-276467
AMPKphosphorylation
up-regulates
→
HIPK2
PSer121		phosphorylation
down-regulates
⊣		HIPK223871434SIGNOR-275483
PRKAA2phosphorylation
up-regulates
→
HIPK2
PSer121		phosphorylation
down-regulates
⊣		HIPK223871434SIGNOR-275486
Regulator Mechanism/Effect Target SIGNOR-ID
PRKAA1phosphorylation
→
up-regulates activity 		HIPK2SIGNOR-276467
AMPKphosphorylation
→
down-regulates activity 		HIPK2SIGNOR-275483
PRKAA2phosphorylation
→
down-regulates activity 		HIPK2SIGNOR-275486