| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| WNK3 | SLC12A5 | – | phosphorylation down-regulates activity | 21613606 | SIGNOR-264628 | |
| WNK1 | SLC12A5 | – | phosphorylation down-regulates activity | 23300475 | SIGNOR-280163 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| WNK3 | phosphorylation → down-regulates activity | SLC12A5 | SIGNOR-264628 |
| WNK1 | phosphorylation → down-regulates activity | SLC12A5 | SIGNOR-280163 |