Entity Details

Name TXNIP
ID Q9H3M7
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AMPKTXNIPSer308
View in OncoXplorer
GLSSRTSsMASRTSSphosphorylation
down-regulates quantity by destabilization		23453806SIGNOR-276489
MAPK1TXNIPThr349
View in OncoXplorer
HRLESPTtPLLDDMDphosphorylation
down-regulates quantity by destabilization		31320475SIGNOR-277468
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AMPKphosphorylation
up-regulates
→
TXNIP
PSer308		phosphorylation
down-regulates
⊣		TXNIP23453806SIGNOR-276489
MAPK1phosphorylation
up-regulates
→
TXNIP
PThr349		phosphorylation
down-regulates
⊣		TXNIP31320475SIGNOR-277468
Regulator Mechanism/Effect Target SIGNOR-ID
AMPKphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TXNIPSIGNOR-276489
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TXNIPSIGNOR-277468