| Name | HIPK3 |
| ID | Q9H422 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 197-525 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK3 | HSF1 | – | phosphorylation up-regulates activity | 18793336 | SIGNOR-279054 | |
| HIPK3 | FADD | Ser194 | QNRSGAMsPMSWNSD | phosphorylation down-regulates activity | 11034606 | SIGNOR-251272 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK3 | phosphorylation up-regulates → | FADD PSer194 | phosphorylation down-regulates ⊣ | FADD | 11034606 | SIGNOR-251272 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| HIPK3 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-279054 |
| HIPK3 | phosphorylation → down-regulates activity | FADD | SIGNOR-251272 |