Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CyclinB/CDK1	ECT2	Thr846	RAFSFSKtPKRALRR	phosphorylation up-regulates	16247472	SIGNOR-216928
CDK1	ECT2	Thr846	RAFSFSKtPKRALRR	phosphorylation up-regulates	16247472	SIGNOR-141179
PLK1	ECT2	–		phosphorylation up-regulates activity	17488623	SIGNOR-279553
CDK1	ECT2	Thr444 View in OncoXplorer	TKSSKSStPVPSKQS	phosphorylation up-regulates	16247472	SIGNOR-141175
CyclinB/CDK1	ECT2	Thr373 View in OncoXplorer	VSMLSLNtPNSNRKR	phosphorylation down-regulates	16170345	SIGNOR-216864
PRKCI	ECT2	Thr359 View in OncoXplorer	YLYEKANtPELKKSV	phosphorylation up-regulates	21189248	SIGNOR-170790
CDK1	ECT2	Thr373 View in OncoXplorer	VSMLSLNtPNSNRKR	phosphorylation down-regulates	16170345	SIGNOR-140549

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CyclinB/CDK1	phosphorylation up-regulates →	ECT2 PThr846	phosphorylation up-regulates →	ECT2	16247472	SIGNOR-216928
CDK1	phosphorylation up-regulates →	ECT2 PThr846	phosphorylation up-regulates →	ECT2	16247472	SIGNOR-141179
CDK1	phosphorylation up-regulates →	ECT2 PThr444	phosphorylation up-regulates →	ECT2	16247472	SIGNOR-141175
CyclinB/CDK1	phosphorylation up-regulates →	ECT2 PThr373	phosphorylation down-regulates ⊣	ECT2	16170345	SIGNOR-216864
PRKCI	phosphorylation up-regulates →	ECT2 PThr359	phosphorylation up-regulates →	ECT2	21189248	SIGNOR-170790
CDK1	phosphorylation up-regulates →	ECT2 PThr373	phosphorylation down-regulates ⊣	ECT2	16170345	SIGNOR-140549

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CyclinB/CDK1	phosphorylation → up-regulates	ECT2	SIGNOR-216928
CDK1	phosphorylation → up-regulates	ECT2	SIGNOR-141179
PLK1	phosphorylation → up-regulates activity	ECT2	SIGNOR-279553
CDK1	phosphorylation → up-regulates	ECT2	SIGNOR-141175
CyclinB/CDK1	phosphorylation down-regulates	ECT2	SIGNOR-216864
PRKCI	phosphorylation → up-regulates	ECT2	SIGNOR-170790
CDK1	phosphorylation down-regulates	ECT2	SIGNOR-140549