| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | ECT2 | Thr846 | RAFSFSKtPKRALRR | phosphorylation up-regulates | 16247472 | SIGNOR-216928 |
| CDK1 | ECT2 | Thr846 | RAFSFSKtPKRALRR | phosphorylation up-regulates | 16247472 | SIGNOR-141179 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | ECT2 PThr846 | phosphorylation up-regulates → | ECT2 | 16247472 | SIGNOR-216928 |
| CDK1 | phosphorylation up-regulates → | ECT2 PThr846 | phosphorylation up-regulates → | ECT2 | 16247472 | SIGNOR-141179 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation → up-regulates | ECT2 | SIGNOR-216928 |
| CDK1 | phosphorylation → up-regulates | ECT2 | SIGNOR-141179 |
