| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | ECT2 | Thr373 | VSMLSLNtPNSNRKR | phosphorylation down-regulates | 16170345 | SIGNOR-216864 |
| CDK1 | ECT2 | Thr373 | VSMLSLNtPNSNRKR | phosphorylation down-regulates | 16170345 | SIGNOR-140549 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | ECT2 PThr373 | phosphorylation down-regulates ⊣ | ECT2 | 16170345 | SIGNOR-216864 |
| CDK1 | phosphorylation up-regulates → | ECT2 PThr373 | phosphorylation down-regulates ⊣ | ECT2 | 16170345 | SIGNOR-140549 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation down-regulates | ECT2 | SIGNOR-216864 |
| CDK1 | phosphorylation down-regulates | ECT2 | SIGNOR-140549 |
