Entity Details

Name NANOG
ID Q9H9S0
Role substrate
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTK2NANOGTyr174QKASAPTyPSLYSSYphosphorylation
up-regulates activity		22493428SIGNOR-276410
PRKCENANOGThr200LPMWSNQtWNNSTWSphosphorylation
up-regulates activity		23708658SIGNOR-278203
PRKCENANOGThr280GLNVIQQtTRYFSTPphosphorylation
up-regulates activity		23708658SIGNOR-278202
MAPK3NANOGSer52MPHTETVsPLPSSMDphosphorylation
down-regulates		24793005SIGNOR-278487
PTK2NANOGTyr35ICGPEENyPSLQMSSphosphorylation
up-regulates activity		22493428SIGNOR-276409
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTK2phosphorylation
up-regulates
→
NANOG
PTyr174		phosphorylation
up-regulates
→		NANOG22493428SIGNOR-276410
PRKCEphosphorylation
up-regulates
→
NANOG
PThr200		phosphorylation
up-regulates
→		NANOG23708658SIGNOR-278203
PRKCEphosphorylation
up-regulates
→
NANOG
PThr280		phosphorylation
up-regulates
→		NANOG23708658SIGNOR-278202
MAPK3phosphorylation
up-regulates
→
NANOG
PSer52		phosphorylation
down-regulates
⊣		NANOG24793005SIGNOR-278487
PTK2phosphorylation
up-regulates
→
NANOG
PTyr35		phosphorylation
up-regulates
→		NANOG22493428SIGNOR-276409
Regulator Mechanism/Effect Target SIGNOR-ID
PTK2phosphorylation
→
up-regulates activity 		NANOGSIGNOR-276410
PRKCEphosphorylation
→
up-regulates activity 		NANOGSIGNOR-278203
PRKCEphosphorylation
→
up-regulates activity 		NANOGSIGNOR-278202
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates 		NANOGSIGNOR-278487
PTK2phosphorylation
→
up-regulates activity 		NANOGSIGNOR-276409