Entity Details

Name EML4
ID Q9HC35
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
NEK7EML4Ser144
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QSPQIRAsPSPQPSSphosphorylation
down-regulates activity		31409757SIGNOR-279237
NEK6EML4Ser146
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PQIRASPsPQPSSQPphosphorylation
down-regulates activity		31409757SIGNOR-279236
NEK7EML4Ser146
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PQIRASPsPQPSSQPphosphorylation
up-regulates activity		31409757SIGNOR-273884
NEK6EML4Ser144
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QSPQIRAsPSPQPSSphosphorylation
up-regulates activity		31409757SIGNOR-273883
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
NEK7phosphorylation
up-regulates
→
EML4
PSer144		phosphorylation
down-regulates
⊣		EML431409757SIGNOR-279237
NEK6phosphorylation
up-regulates
→
EML4
PSer146		phosphorylation
down-regulates
⊣		EML431409757SIGNOR-279236
NEK7phosphorylation
up-regulates
→
EML4
PSer146		phosphorylation
up-regulates
→		EML431409757SIGNOR-273884
NEK6phosphorylation
up-regulates
→
EML4
PSer144		phosphorylation
up-regulates
→		EML431409757SIGNOR-273883
Regulator Mechanism/Effect Target SIGNOR-ID
NEK7phosphorylation
→
down-regulates activity 		EML4SIGNOR-279237
NEK6phosphorylation
→
down-regulates activity 		EML4SIGNOR-279236
NEK7phosphorylation
→
up-regulates activity 		EML4SIGNOR-273884
NEK6phosphorylation
→
up-regulates activity 		EML4SIGNOR-273883