Entity Details

Name NEK6
ID Q9HC98
Role substrate
Enzymatic Domains
Protein kinase 45-310
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CHEK2NEK6–phosphorylation
down-regulates activity		18728393SIGNOR-279404
NEK9NEK6Ser206
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SETTAAHsLVGTPYYphosphorylation
up-regulates activity		12840024SIGNOR-102996
CHEK1NEK6–phosphorylation
down-regulates activity		18728393SIGNOR-279403
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
NEK9phosphorylation
up-regulates
→
NEK6
PSer206		phosphorylation
up-regulates
→		NEK612840024SIGNOR-102996
Regulator Mechanism/Effect Target SIGNOR-ID
CHEK2phosphorylation
→
down-regulates activity 		NEK6SIGNOR-279404
NEK9phosphorylation
→
up-regulates activity 		NEK6SIGNOR-102996
CHEK1phosphorylation
→
down-regulates activity 		NEK6SIGNOR-279403