| Name | CSNK1G1 |
| ID | Q9HCP0 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 44-315 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1G1 | LRP6 | Thr1479 | SSSSTKGtYFPAILN | phosphorylation up-regulates | 16341016 | SIGNOR-143029 |
| CSNK1G1 | LYN | Ser13 | SKGKDSLsDDGVDLK | phosphorylation up-regulates quantity by stabilization | 33004926 | SIGNOR-275396 |
| CSNK1G1 | FOXO1 | Ser322 | PRTSSNAsTISGRLS | phosphorylation down-regulates activity | 11980723 | SIGNOR-250822 |
| CSNK1G1 | FOXO1 | Ser325 | SSNASTIsGRLSPIM | phosphorylation down-regulates activity | 11980723 | SIGNOR-250821 |
| CSNK1G1 | FOXO | Ser322 | PRTSSNAsTISGRLS | phosphorylation down-regulates activity | 11980723 | SIGNOR-252901 |
| CSNK1G1 | FOXO | Ser325 | SSNASTIsGRLSPIM | phosphorylation down-regulates activity | 11980723 | SIGNOR-252902 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1G1 | phosphorylation up-regulates → | LRP6 PThr1479 | phosphorylation up-regulates → | LRP6 | 16341016 | SIGNOR-143029 |
| CSNK1G1 | phosphorylation up-regulates → | LYN PSer13 | phosphorylation up-regulates → | LYN | 33004926 | SIGNOR-275396 |
| CSNK1G1 | phosphorylation up-regulates → | FOXO1 PSer322 | phosphorylation down-regulates ⊣ | FOXO1 | 11980723 | SIGNOR-250822 |
| CSNK1G1 | phosphorylation up-regulates → | FOXO1 PSer325 | phosphorylation down-regulates ⊣ | FOXO1 | 11980723 | SIGNOR-250821 |
| CSNK1G1 | phosphorylation up-regulates → | FOXO PSer322 | phosphorylation down-regulates ⊣ | FOXO | 11980723 | SIGNOR-252901 |
| CSNK1G1 | phosphorylation up-regulates → | FOXO PSer325 | phosphorylation down-regulates ⊣ | FOXO | 11980723 | SIGNOR-252902 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK1G1 | phosphorylation → up-regulates | LRP6 | SIGNOR-143029 |
| CSNK1G1 | phosphorylation → up-regulates quantity by stabilization | LYN | SIGNOR-275396 |
| CSNK1G1 | phosphorylation → down-regulates activity | FOXO1 | SIGNOR-250822 |
| CSNK1G1 | phosphorylation → down-regulates activity | FOXO1 | SIGNOR-250821 |
| CSNK1G1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252901 |
| CSNK1G1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252902 |