Entity Details

Name SH2D2A
ID Q9NP31
Role substrate
Enzymatic Domains
SH2 95-186
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LCKSH2D2ATyr280PKPSNPIyNEPDEPIphosphorylation
up-regulates activity		18541536SIGNOR-262888
LCKSH2D2ATyr305GEAPSNIyVEVEDEGphosphorylation
up-regulates activity		18541536SIGNOR-262890
LCKSH2D2ATyr290PDEPIAFyAMGRGSPphosphorylation
up-regulates activity		18541536SIGNOR-262889
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LCKphosphorylation
up-regulates
→
SH2D2A
PTyr280		phosphorylation
up-regulates
→		SH2D2A18541536SIGNOR-262888
LCKphosphorylation
up-regulates
→
SH2D2A
PTyr305		phosphorylation
up-regulates
→		SH2D2A18541536SIGNOR-262890
LCKphosphorylation
up-regulates
→
SH2D2A
PTyr290		phosphorylation
up-regulates
→		SH2D2A18541536SIGNOR-262889
Regulator Mechanism/Effect Target SIGNOR-ID
LCKphosphorylation
→
up-regulates activity 		SH2D2ASIGNOR-262888
LCKphosphorylation
→
up-regulates activity 		SH2D2ASIGNOR-262890
LCKphosphorylation
→
up-regulates activity 		SH2D2ASIGNOR-262889