| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | GCM1 | Ser322 | NYPFPLTsWPCSFSP | phosphorylation down-regulates quantity by destabilization | 20855292 | SIGNOR-278940 |
| CAMK1 | GCM1 | Ser47 | YAKHIYSsEDKNAQR | phosphorylation up-regulates activity | 21791615 | SIGNOR-262680 |
| DUSP23 | GCM1 | Ser322 | NYPFPLTsWPCSFSP | dephosphorylation up-regulates quantity by stabilization | 20855292 | SIGNOR-276982 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | GCM1 PSer322 | phosphorylation down-regulates ⊣ | GCM1 | 20855292 | SIGNOR-278940 |
| CAMK1 | phosphorylation up-regulates → | GCM1 PSer47 | phosphorylation up-regulates → | GCM1 | 21791615 | SIGNOR-262680 |
| DUSP23 | dephosphorylation down-regulates ⊣ | GCM1 PSer322 | dephosphorylation down-regulates ⊣ | GCM1 | 20855292 | SIGNOR-276982 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | GCM1 | SIGNOR-278940 |
| CAMK1 | phosphorylation → up-regulates activity | GCM1 | SIGNOR-262680 |
| DUSP23 | dephosphorylation → up-regulates quantity by stabilization | GCM1 | SIGNOR-276982 |