Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MKNK1	PNPLA8	Ser511	ELYRKLGsDVFSQNV	phosphorylation up-regulates activity	23258543	SIGNOR-273677

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MKNK1	phosphorylation up-regulates →	PNPLA8 PSer511	phosphorylation up-regulates →	PNPLA8	23258543	SIGNOR-273677

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MKNK1	phosphorylation → up-regulates activity	PNPLA8	SIGNOR-273677