| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | POLM | Ser12 | RRRARVGsPSGDAAS | phosphorylation down-regulates activity | 23933132 | SIGNOR-273597 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation up-regulates → | POLM PSer12 | phosphorylation down-regulates ⊣ | POLM | 23933132 | SIGNOR-273597 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation → down-regulates activity | POLM | SIGNOR-273597 |