| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKC | KCNK9 | Thr341 | IEEISPStLKNSLFP | phosphorylation down-regulates activity | 17374744 | SIGNOR-276059 |
| PRKACA | KCNK9 | Ser373 | RLMKRRKsV | phosphorylation up-regulates | 21357689 | SIGNOR-172466 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKC | phosphorylation up-regulates → | KCNK9 PThr341 | phosphorylation down-regulates ⊣ | KCNK9 | 17374744 | SIGNOR-276059 |
| PRKACA | phosphorylation up-regulates → | KCNK9 PSer373 | phosphorylation up-regulates → | KCNK9 | 21357689 | SIGNOR-172466 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PKC | phosphorylation → down-regulates activity | KCNK9 | SIGNOR-276059 |
| PRKACA | phosphorylation → up-regulates | KCNK9 | SIGNOR-172466 |
